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By: M. Gambal, M.A., M.D.

Program Director, Lewis Katz School of Medicine, Temple University

In this regard the Law of Time frames the cyclic recurrence of the otherwise irregular 12:60 Gregorian calendar by the intrinsic formulation 28:7 bacteria mod 164 buy discount colchicine online. That is bacteria battery generic 0.5mg colchicine, just as the 19:7 factor coordinates the lunar calendars every nineteen years antibiotic resistance in veterinary medicine cheap colchicine express, there being seven intercalations of the thirteenth moon during that cycle, so in the Gregorian calendar every twenty-eight years there are always exactly seven leap days and years. Understanding a calendar as the instrument that locks the conditioned programs of a given culture or people into place, we can now understand how the unconscious metaprogram of the macro-organizing principle of the Gregorian calendar cumula tively recycles all its millennial programs every twenty-eight years. Since its incep tion in 1582, the Gregorian calendar has been dragging forward a host of condi tioned thought forms and perceptions, including those inherited from 1,500 years of the Julian calendar that it had reformed. At points of dramatic break in the continu ity of human consciousness, a new set of cycles is set to recur. The entirety of the mind field conditioned and held in place by the Gregorian calendar then reaches its full frui tion during the two subsequent 28-year cycles, fifty-six years in all-thus bringing forward two millennia of conditionings, conflicts, and unconscious death wishes or apocalyptic programs. The first cycle was initiated in the year 1945, the year in which Vernadsky died, the atomic bomb was tested once and used twice, and the Second World War came to an end. It is most telling that the Second World War was concluded at the beginning of this 56-year cycle of the technosphere, for it was a war concluded not with peace but with instruments of mass destruction and terror. The technosphere has its origins with the full capture of the human mental field by the 12:60 frequency in 1618. From 1618 onward, the noosphere is increasingly obscured by a mental field known as the technospheric sheath. It is important to note that the Julian count, the basis of all modern scientific calculations, is a scale created by Thomas Scaliger in 1583, twenty one years after the 1562 Mayan book burning. This linear time scale, like the Gregorian calendar reform itself, was intended to co-opt the Mayan thirteen baktun Long Count by setting a count of days that begins the first of January, 4713 B. This deliberate historical act, the Julian count, along with the Gregorian calendar and the mechanical clock, established the paradigmatic notion of the linearity of time in the ripening field of scientific thought. Reflected in the noosphere, this linear, irreversible time concept levels and stunts the realization of human mass consciousness. In fact, during the technospheric cycle, especially after 1754, the ceiling of human conscious ness is maintained by a preoccupation with mechanistic third-dimensional operations while becoming increasingly alienated from the organic order of reality. This creates the 12:60 consciousness constant, a mental ceiling that actually diminishes in propor tion to the increasing rates of multiplication, propagation, and intrinsic velocity of the machine. The industrial sheath spreads throughout the biosphere between 1754 and 1901, the official beginning of the twentieth century. During this critical stage of the proto-technosphere, the actions of human behavior interacting with machine technology make the expression of true culture increasingly difficult, if not impos sible. Civilization becomes a set of symbols purveyed through museums, galleries, and theaters, and recorded and reproduced in ever more advanced technological forms. But what of culture, which is not the same as civilization-what becomes of culture? According to the common dictionary definition, which already reflects the mass mind, technology is "the totality of the means employed to provide objects necessary for human suste nance and comfort. In common parlance, therefore, technology refers to the complex apparatus of mechanization. The Climax of History convert human labor into processes carried out purely by machine-oriented or me chanical means. This is also inclusive of the entirety of computer technology, which represents the mechanization of the more purely mental processes of thought and communication. Mechanization, we must remember, originated in the clock, in the mechanization of time. It is the mechanization of time that presupposes the tendency toward mecha nization as a state of mind within the noosphere. Since artificial time is characterized by the illusion of an inexorable and irreversible linearity, the compulsion toward materialism is also experienced in the same way, an inexorable motion spearheaded by the advance of ever more improved machines. The machines themselves are the products and means of industrialization-the technological transformation of raw goods into consumer goods, a process accounting for much of the free energy intro duced into the biogeochemical combustion of the biosphere. Inseparable from mechanized technology, too, are materialism and the con cept of the World Market and, more recently, of globalization. Materialism is im plicit in the dictionary definition of technology as the means employed not only for human sustenance but also for human comfort. This comfort can only be of a material form or nature, hence the pursuit of comfort through mechanized tech nology can only be for the furtherance of a philosophy and exaggerated lifestyle of materialism-the belief that only the material things of this world have any value.

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Viral Infections of the Gastrointestinal Tract: Second Edition bacteria that causes pink eye discount colchicine 0.5mg otc, Revised and Expanded vyrus 985 c3 purchase colchicine online from canada, edited by Albert Z virus classification discount 0.5mg colchicine overnight delivery. Development and Clinical Uses of Haemophilus b Conjugate Vaccines, edited by Ronald W. New Macrolides, Azalides, and Streptogramins in Clinical Practice, edited by Harold C. Expanding Indications for the New Macrolides, Azalides, and Streptogramins, edited try Stephen H. New Considerations for Macrolides, Azalides, Streptogramins, and Ketolides, edited by Stephen H. Antimicrobial Pharmacodynamics in Theory and Clinical Practice, edited by Charles H. Pediatric Anaerobic Infections: Diagnosis and Management, Third Edition, Revised and Expanded, Itzhak Brook 30. Viral Infections and Treatment, edited by Helga Ruebsamen-Waigmann, Karl Deres, Guy Hewlett, and Reinhotd Welker 31. Catheter-Related Infections: Second Edition, edited by Harald Seifert, Bernd Jansen, and Barry Farr 33. Infection Management for Geriatrics in Long-Term Care Facilities, Second Edition, edited by Thomas T. Infective Endocarditis: Management in the Era of Intravascular Devices, edited by John L. Antimicrobial Pharmacodynamics in Theory and Clinical Practice, Second Edition, edited by Charles H. Antimicrobial Resistance: Problem Pathogens and Clinical Countermeasures, edited by Robert C. Jerome University of Washington Fred Hutchinson Cancer Research Center Seattle, Washington, U. Government works Printed on acid-free paper 10987654321 International Standard Book Number-10: 1-4200-8495-X (Hardcover) International Standard Book Number-13: 978-1-4200-8495-5 (Hardcover) Thisbookcontainsinformationobtainedfromauthenticandhighlyregardedsources. Reasonable efforts have been made to publish reliable data and information, but the author and the publisher cannot assume responsibility for the validity of all materials or for the consequence of their use. No part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, micro? For permission to photocopy or use material electronically from this work, please access Trademark Notice: Product or corporate names may be trademarks or registered trademarks, and are used only for identi? Lennette: A Tribute Ed Lennette was born in Pittsburgh, Pennsylvania, on September 11, 1908, and died of respira tory failure on October 1, 2000, following surgery. These cold, hard facts in no way describe or tell us anything useful about this man and his accomplished life. When that laboratory was transferred to the California Department of Public Health in 1947, Ed became its Director, following a year as Chief of the Medical-Veterinary division of the U. For the next 31 years he molded this laboratory into a world-renowned training laboratory, as well as a, perhaps the, leading laboratory for the diagnosis of viral and rickettsial diseases. He also served as a consultant to many government agencies and participated in numerous advisory committees. Among them was Diagnostic Procedures for Viral, Rickettsial, and Chlamydial Infections,? coedited with Drs. After he retired from public service in 1978, Ed became the President of the California Public Health Foundation, and in 1981 and 1982, served as Acting Director of the W. Lennette and his legendary accomplishments, but it was only in the 1980s that we met for the? Awed by meeting such a senior person and eminent scientist, Ed put me at ease immediately. To the end he strongly supported gaining experience that leads us to knowledge, as opposed to exclusively technical procedures, relied on by some in the rapidly moving? Ed was tough; he didn?t take any guff from anyone, although he usually was diplomatic and always polite. He had a marvelous sense of humor, and he was socially adventurous, generous of his time, and patient with young people.

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This problem-solving mind-work? occurs at the 59 knowledge-based level (conscious mode) antibiotic 825 buy 0.5mg colchicine free shipping. The 60 flowchart illustrates the distinctions between the three levels of performance antibiotic resistance funding order colchicine with a visa. Since the worker is highly Pre-packaged actionsPre-packaged actionsPre-packaged actionsPre-packaged actionsPre-packaged actionsPre-packaged actions RecognizeRecognizeRecognizeRecognizeRecognizeRecognizeRecognizeRecognizeRecognizeRecognize determine bydetermine bydetermine bydetermine bydetermine bydetermine by NoNoNoNo Solved? If infection from bug bite generic colchicine 0.5mg with amex, as a result of applying the action rule, the problem is solved, the worker will then return to the original skill-based sequence. If the problem is not resolved, then further information may be gathered in order to try to identify a pattern of symptoms corresponding to a known cause. If the cause of the problem cannot be established by applying any available rule, the worker may then have to revert to the knowledge based level. It may become necessary to utilize chemical or engineering knowledge to handle 61 the situation. As shown in the above example, uncertainty declines as knowledge about a situation improves (learning and practice). Consequently, familiarity (knowledge, skill, and experience) with a task will establish the level of attention or mental functions the individual chooses to perform an activity. As uncertainty increases, people tend to focus their attention to better detect critical information needed for the situation. People want to boost their understanding of a situation in 62 order to respond correctly. Skill-Based Performance HighHighHighHighHighHighHigh Skill-based performance involves highly practiced,? Behavior is governed by preprogrammed instructions developed by either training or experience LowLowLowLowLowLowLow InattentionInattentionInattentionInattentionInattention and is less dependent upon 63 LowLowLowLowLowLowLow HighHighHighHighHighHighHigh external conditions. FamiliarityFamiliarityFamiliarityFamiliarityFamiliarityFamiliarity (w/ task)(w/ task)(w/ task)(w/ task)(w/ task)(w/ task) Information that can be processed with little or no allocation of attention resources is called automatic processing. When skills are learned to the point of being automatic, the load on working memory typically is 64 reduced by 90 percent. This occurs after extensive practice of a task so that, literally, it can be performed without thought. In the skill-based mode, the individual is able to function very effectively by using pre-programmed sequences of behavior that do not require much conscious control. It is only occasionally 65 necessary to check on progress at particular points when operating in this mode. Error Modes are the prevalent ways, not the only ways, people err for the particular performance mode. Error modes are generalities that aid in anticipating and managing error likely situations aggravated by inattention, misinterpretation, and inaccurate mental models. Skill-Based Error Mode Inattention the error mode for skill-based performance is inattention. Skill-based errors are primarily execution errors, involving action slips and lapses in attention or concentration. Errors involve inadvertent slips and unintentional omissions triggered by simple human variability or by not recognizing changes (note the? Some examples of errors committed while in the skill-based performance level follow. The hydraulic system was being worked on, and the electrician was aware that it would be unsafe to activate the system. Nevertheless, after changing the bulb, and before he had realized what he was doing, he had followed his usual routine and pushed the switch to the on? position to test whether the light was now working. People most often possess an accurate understanding of the task and have correct intentions. However, only 25 percent of all errors are attributable to skill-based 68 errors in the nuclear power industry. Potentially, a person can be so focused on a skill-based 69 task that important information in the work place is not detected. The greater the familiarity, the less likely perceived risk will match actual risk. People become comfortable with risk and eventually grow 70 insensitive to hazards.

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Hence antibiotic beginning with c order colchicine 0.5 mg online, these comorbidities might not apply to antimicrobial laundry soap generic colchicine 0.5mg with visa all individuals who qualify for a diagnosis of exhibitionistic disorder virus d68 symptoms purchase 0.5 mg colchicine. Conditions that occur comorbidly with exhibitionistic disorder at high rates include depressive, bipolar, anxiety, and substance use disorders; hypersexuality; attention-deficit/hyperactivity disorder; other paraphilic disorders; and antisocial personality disorder. Over a period of at least 6 months, recurrent and intense sexual arousal from touching or rubbing against a nonconsenting person, as manifested by fantasies, urges, or be? haviors. Specify if: In a controlled environment: this specifier is primarily applicable to individuals living in institutional or other settings where opportunities to touch or rub against a noncon? senting person are restricted. Specifiers the "in remission" specifier does not address the continued presence or absence of frot teurism per se, which may still be present after behaviors and distress have remitted. Diagnostic Features the diagnostic criteria for frotteuristic disorder can apply both to individuals who relatively freely disclose this paraphilia and to those who firmly deny any sexual attraction from touch? ing or rubbing against a nonconsenting individual regardless of considerable objective evi? dence to the contrary. If disclosing individuals also report psychosocial impairment due to their sexual preferences for touching or rubbing against a nonconsenting individual, they could be diagnosed with frotteuristic disorder. In contrast, if they declare no distress (demon? strated by lack of anxiety, obsessions, guilt, or shame) about these paraphilic impulses and are not impaired in other important areas of functioning because of this sexual interest, and their psychiatric or legal histories indicate that they do not act on it, they could be ascertained as having frotteuristic sexual interest but should not be diagnosed with frotteuristic disorder. Nondisclosing individuals include, for instance, individuals known to have been touching or rubbing against nonconsenting individuals on separate occasions but who contest any urges or fantasies concerning such sexual behavior. Such individuals may re? port that identified episodes of touching or rubbing against an unwilling individual were all unintentional and nonsexual. Others may disclose past episodes of touching or rubbing against nonconsenting individuals but contest any major or persistent sexual interest in this. Since these individuals deny having fantasies or impulses about touching or rubbing, they would consequently reject feeling distressed or psychosocially impaired by such impulses. Despite their nondisclosing position, such individuals may be diagnosed with frotteuristic disorder. Recurrent frotteuristic behavior constitutes satisfactory support for frotteurism (by fulfilling Criterion A) and concurrently demonstrates that this paraphili cally motivated behavior is causing harm to others (by fulfilling Criterion B). Note that multiple victims are a sufficient but not a nec? essary condition for diagnosis; criteria may also be met if the individual acknowledges in? tense frotteuristic sexual interest with clinically significant distress and/or impairment. The Criterion A time frame, indicating that signs or symptoms of frotteurism must persist for at least 6 months, should also be inte? Hence, the duration part of Criterion A may also be met if there is clear evidence of recurrent behaviors or distress over a shorter but nontransient time period. Prevaience Frotteuristic acts, including the uninvited sexual touching of or rubbing against another individual, may occur in up to 30% of adult males in the general population. Approximately 10%-14% of adult males seen in outpatient settings for paraphilic disorders and hypersex? uality have a presentation that meets diagnostic criteria for frotteuristic disorder. Hence, whereas the population prevalence of frotteuristic disorder is unknown, it is not likely that it exceeds the rate found in selected clinical settings. Development and Course Adult males with frotteuristic disorder often report first becoming aware of their sexual in? terest in surreptitiously touching unsuspecting persons during late adolescence or emerging adulthood. However, children and adolescents may also touch or rub against unwilling oth? ers in the absence of a diagnosis of frotteuristic disorder. Although there is no minimum age for the diagnosis, frotteuristic disorder can be difficult to differentiate from conduct-disor? dered behavior without sexual motivation in individuals at younger ages. Frotteuristic disorder, however, by definition requires one or more contributing factors that may change over time with or without treatment: subjec? tive distress. As with other sexual preferences, advanc? ing age may be associated with decreasing frotteuristic sexual preferences and behavior. Nonsexual antisocial behavior and sexual preoccupation/hypersexuality might be nonspecific risk factors, although the causal relationship to frotteurism is uncertain and the specificity unclear. However, frotteurism is a necessary precondition for frotteuristic disorder, so risk factors for frotteurism should also increase the rate of frotteuristic disorder. G ender-Related Diagnostic Issues There appear to be substantially fewer females with frotteuristic sexual preferences than males. Conduct disorder in adolescents and antisocial personality disorder would be characterized by additional norm-breaking and antisocial behaviors, and the specific sexual interest in touching or rubbing against a nonconsenting individual should be lacking. Substance use disorders, particularly those involving stimu? lants such as cocaine and amphetamines, might involve single frotteuristic episodes by in? toxicated individuals but should not involve the typical sustained sexual interest in touching or rubbing against unsuspecting persons.

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